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1

Immunometabolism and HIV-1 pathogenesis: food for thought

SÃ¡ez-CiriÃ³n, Asier, Sereti, Irini

Journal:

Nature Reviews Immunology

Year:

2020

File:

PDF, 2.50 MB

2020

2

Initiation of ART during Early Acute HIV Infection Preserves Mucosal Th17 Function and Reverses HIV-Related Immune Activation

Schuetz, Alexandra, Deleage, Claire, Sereti, Irini, Rerknimitr, Rungsun, Phanuphak, Nittaya, Phuang-Ngern, Yuwadee, Estes, Jacob D., Sandler, Netanya G., Sukhumvittaya, Suchada, Marovich, Mary, Jongra

Journal:

Year:

2014

Language:

english

File:

PDF, 1.29 MB

english, 2014

3

Immune activation and HIV

Sereti, Irini, Altfeld, Marcus

Journal:

Current Opinion in HIV and AIDS

Year:

2016

Language:

english

File:

PDF, 122 KB

english, 2016

4

Obesity is associated with greater inflammation and monocyte activation among HIV-infected adults receiving antiretroviral therapy

Conley, Lois J., Bush, Timothy J., Rupert, Adam W., Sereti, Irini, Patel, Pragna, Brooks, John T., Baker, Jason V.

Journal:

Year:

2015

Language:

english

File:

PDF, 293 KB

english, 2015

5

The Effect of Intermittent IL-2 Therapy on CD4 T Cells in the Gut in HIV-1–Infected Patients

Read, Sarah W, Ciccone, Emily J, Mannon, Peter J, Yao, Michael D, Chairez, Cheryl L, Davey, Richard T, Kovacs, Joseph A, Sereti, Irini

Journal:

JAIDS Journal of Acquired Immune Deficiency Syndromes

Year:

2011

Language:

english

File:

PDF, 272 KB

english, 2011

6

Interleukin-2 induced immune effects in human immunodeficiency virus-infected patients receiving intermittent interleukin-2 immunotherapy

Joseph A. Kovacs, Susan Vogel, Julia A. Metcalf, Michael Baseler, Randy Stevens, Joseph Adelsberger, Richard Lempicki, Richard L. Hengel, Irini Sereti, Laurie Lambert, Robin L. Dewar, Richard T. Davey

Journal:

European Journal of Immunology

Year:

2001

Language:

english

File:

PDF, 268 KB

english, 2001

7

IL-15 acts as a potent inducer of CD4+CD25hi cells expressing FOXP3

Hiromi Imamichi, Irini Sereti, H. Clifford Lane

Journal:

European Journal of Immunology

Year:

2008

Language:

english

File:

PDF, 517 KB

english, 2008

8

Complement Activation by HIV-1-Infected Target Cells Enhances IL-2-Stimulated but Not Unstimulated ADCC Activity Mediated by peripheral Blood Mononuclear Cells

Irini Sereti, Gregory T. Spear

Journal:

Clinical Immunology and Immunopathology

Year:

1996

Language:

english

File:

PDF, 167 KB

english, 1996

9

d-Dimer and CRP levels are elevated prior to antiretroviral treatment in patients who develop IRIS

Brian O. Porter, G. Laissa Ouedraogo, Jessica N. Hodge, Margo A. Smith, Alice Pau, Gregg Roby, Richard Kwan, Rachel J. Bishop, Catherine Rehm, JoAnn Mican, Irini Sereti

Journal:

Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 327 KB

english, 2010

10

Corrigendum to “D-Dimer and CRP levels are elevated prior to antiretroviral treatment in patients who develop IRIS” [Clin. Immunol. 136 (2010) 42–50]

Brian O. Porter, G. Laissa Ouedraogo, Jessica N. Hodge, Margo A. Smith, Alice Pau, Gregg Roby, Richard Kwan, Rachel J. Bishop, Catherine Rehm, JoAnn Mican, Irini Sereti

Journal:

Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 139 KB

english, 2010

11

Interleukin 2 Leads to Dose-Dependent Expression of the Alpha Chain of the IL-2 Receptor on CD25-Negative T Lymphocytes in the Absence of Exogenous Antigenic Stimulation

Irini Sereti, Juan Gea-Banacloche, Min-Ying Kan, Claire W. Hallahan, H.Clifford Lane

Journal:

Clinical Immunology

Year:

2000

Language:

english

File:

PDF, 324 KB

english, 2000

12

BAY 50-4798, a novel, high-affinity receptor-specific recombinant interleukin-2 analog, induces dose-dependent increases in CD25 expression and proliferation among unstimulated, human peripheral blood mononuclear cells in vitro

Lynn Matthews, Sherita Chapman, Meena S. Ramchandani, H. Clifford Lane, Richard T. Davey Jr., Irini Sereti

Journal:

Clinical Immunology

Year:

2004

Language:

english

File:

PDF, 928 KB

english, 2004

13

PS1-32 Decreased IL-7 responsiveness of T lymphocytes in patients with idiopathic CD4 lymphopenia

Camille E. Puronen, William L. Thompson, Hiromi Imamichi, Stephanie Beq, Jessica N. Hodge, Catherine Rehm, Rebecca DerSimonian, Jason M. Brenchley, Irini Sereti

Journal:

Year:

2010

Language:

english

File:

PDF, 57 KB

english, 2010

14

PL4-2 Cytokine-based therapies in HIV infection: Lessons from IL-2 and expectations from IL-7

Journal:

Year:

2010

Language:

english

File:

PDF, 133 KB

english, 2010

15

Idiopathic CD4+ Lymphocytopenia: Natural History and Prognostic Factors.

Dimitrios Zonios, Judith Falloon, John Bennett, Pamela Shaw, Doreen Chaitt, Michael Polis, Joseph Kovacs, Richard Davey, H. Clifford Lane, Henry Masur, Irini Sereti

Journal:

International Journal of Infectious Diseases

Year:

2008

Language:

english

File:

PDF, 57 KB

english, 2008

16

Serious Non-AIDS events: Immunopathogenesis and interventional strategies

Hsu, Denise C, Sereti, Irini, Ananworanich, Jintanat

Journal:

AIDS Research and Therapy

Year:

2013

Language:

english

File:

PDF, 356 KB

english, 2013

17

Immune restoration after antiretroviral therapy: the pitfalls of hasty or incomplete repairs

Wilson, Eleanor M. P., Sereti, Irini

Journal:

Immunological Reviews

Year:

2013

Language:

english

File:

PDF, 393 KB

english, 2013

18

Cytomegalovirus immune reconstitution inflammatory syndrome manifesting as acute appendicitis in an HIV-infected patient

Faldetta, Kimberly F, Kattakuzhy, Sarah, Wang, Hao-Wei, Sereti, Irini, Sheikh, Virginia

Journal:

BMC Infectious Diseases

Year:

2014

Language:

english

File:

PDF, 215 KB

english, 2014

19

Graves' Disease after Interleukin-2 Therapy in a Patient with Human Immunodeficiency Virus Infection

Jimenez, Camilo, Moran, Stephanie A., Sereti, Irini, Wynne, Sarah, Yen, Paul M., Falloon, Judith, Davey, Richard T., Sarlis, Nicholas J.

Journal:

Year:

2004

Language:

english

File:

PDF, 78 KB

english, 2004

20

Immune reconstitution inflammatory syndrome: the trouble with immunity when you had none

Barber, Daniel L., Andrade, Bruno B., Sereti, Irini, Sher, Alan

Journal:

Nature Reviews Microbiology

Year:

2012

Language:

english

File:

PDF, 455 KB

english, 2012

21

Idiopathic CD4 lymphocytopenia: a case of missing, wandering or ineffective T cells

Dimitrios Zonios,Virginia Sheikh,Irini Sereti

Journal:

Arthritis Research & Therapy

Year:

2012

Language:

english

File:

PDF, 141 KB

english, 2012

22

The Effect of Continuous Versus Pericycle Antiretroviral Therapy on IL-2 Responsiveness

Healey, Letha M., Hahn, Barbara K., Rehm, Catherine A., Adelsberger, Joseph, Qin, Jing, Follmann, Dean A., Tavel, Jorge, Kovacs, Joseph A., Sereti, Irini, Davey, Jr., Richard T.

Journal:

Journal of Interferon & Cytokine Research

Year:

2008

Language:

english

File:

PDF, 1.13 MB

english, 2008

23

Evidence for Translocation of Microbial Products in Patients with Idiopathic CD4 Lymphocytopenia

Lee, Philip I., Ciccone, Emily J., Read, Sarah W., Asher, Ava, Pitts, Robert, Douek, Daniel C., Brenchley, Jason M., Sereti, Irini

Journal:

The Journal of Infectious Diseases

Year:

2009

Language:

english

File:

PDF, 451 KB

english, 2009

24

CD4 T Cell Survival after Intermittent Interleukin‐2 Therapy Is Predictive of an Increase in the CD4 T Cell Count of HIV‐Infected Patients

Read, Sarah W., Lempicki, Richard A., Mascio, Michele Di, Srinivasula, Sharat, Burke, Rosanne, Sachau, William, Bosche, Marjorie, Adelsberger, Joseph W., Sereti, Irini, Davey, Jr., Richard T., Tavel,

Journal:

The Journal of Infectious Diseases

Year:

2008

Language:

english

File:

PDF, 1.37 MB

english, 2008

25

CD4 + T Cell Responses to Interleukin‐2 Administration in HIV‐Infected Patients Are Directly Related to the Baseline Level of Immune Activation

Sereti, Irini, Sklar, Peter, Ramchandani, Meena S., Read, Sarah W., Aggarwal, Vinay, Imamichi, Hiromi, Natarajan, Ven, Metcalf, Julia A., Kovacs, Joseph A., Tavel, Jorge, Davey, Richard T., DerSimonia

Journal:

The Journal of Infectious Diseases

Year:

2007

Language:

english

File:

PDF, 486 KB

english, 2007

26

Can early therapy reduce inflammation?

Sandler, Netanya G., Sereti, Irini

Journal:

Current Opinion in HIV and AIDS

Year:

2014

Language:

english

File:

PDF, 308 KB

english, 2014

27

Plasma interleukin-18 levels are a biomarker of innate immune responses that predict and characterize tuberculosis-associated immune reconstitution inflammatory syndrome

Tan, Hong Yien, Yong, Yean Kong, Andrade, Bruno B., Shankar, Esaki M., Ponnampalavanar, Sasheela, Omar, Sharifah F.S., Narendran, Gopalan, Kamarulzaman, Adeeba, Swaminathan, Soumya, Sereti, Irini, Cro

Journal:

Year:

2015

Language:

english

File:

PDF, 688 KB

english, 2015

28

Acute tubular nephropathy in a patient with acute HIV infection: review of the literature

Ananworanich, Jintanat, Datta, Anandita A, Fletcher, James LK, Townamchai, Natavudh, Chomchey, Nitiya, Kroon, Eugene, Sereti, Irini, Valcour, Victor, Kim, Jerome H

Journal:

AIDS Research and Therapy

Year:

2014

Language:

english

File:

PDF, 770 KB

english, 2014

29

HIV Infection and the Gut: Scarred for Life?

Read, Sarah W., Sereti, Irini

Journal:

The Journal of Infectious Diseases

Year:

2008

Language:

english

File:

PDF, 47 KB

english, 2008

30

A Randomized, Double‐Blinded, Placebo‐Controlled Trial of Intermittent Administration of Interleukin‐2 and Prednisone in Subjects Infected with Human Immunodeficiency Virus

Tavel, Jorge A., Sereti, Irini, Walker, Robert E., Hahn, Barbara, Kovacs, Joseph A., Jagannatha, Shyla, Davey, Jr., Richard T., Falloon, Judith, Polis, Michael A., Masur, Henry, Metcalf, Julia A., Ste

Journal:

The Journal of Infectious Diseases

Year:

2003

Language:

english

File:

PDF, 143 KB

english, 2003

31

Treatment of Progressive Multifocal Leukoencephalopathy With Interleukin 7

Alstadhaug, Karl B., Croughs, Thérèse, Henriksen, Stian, Leboeuf, Céline, Sereti, Irini, Hirsch, Hans H., Rinaldo, Christine Hanssen

Journal:

Year:

2014

Language:

english

File:

PDF, 369 KB

english, 2014

32

Immunopathogenesis of Human Immunodeficiency Virus: Implications for Immune‐Based Therapies

Sereti, Irini, Lane, H. Clifford

Journal:

Clinical Infectious Diseases

Year:

2001

Language:

english

File:

PDF, 505 KB

english, 2001

33

Disseminated Nocardiosis in a Patient with X‐Linked Chronic Granulomatous Disease and Human Immunodeficiency Virus Infection

Sereti, Irini, Holland, Steven M.

Journal:

Clinical Infectious Diseases

Year:

2001

Language:

english

File:

PDF, 192 KB

english, 2001

34

Biomarkers in immune reconstitution inflammatory syndrome: signals from pathogenesis

Sereti, Irini, Rodger, Alison J, French, Martyn A

Journal:

Current Opinion in HIV and AIDS

Year:

2010

Language:

english

File:

PDF, 241 KB

english, 2010

35

Decreases in Colonic and Systemic Inflammation in Chronic HIV Infection after IL-7 Administration

Sereti, Irini, Estes, Jacob D., Thompson, William L., Morcock, David R., Fischl, Margaret A., Croughs, Thérèse, Beq, Stéphanie, Lafaye de Micheaux, Sylvie, Yao, Michael D., Ober, Alexander, Wilson, El

Journal:

Year:

2014

Language:

english

File:

PDF, 1.77 MB

english, 2014

36

Quantifying and Predicting the Effect of Exogenous Interleukin-7 on CD4+T Cells in HIV-1 Infection

Thiébaut, Rodolphe, Drylewicz, Julia, Prague, Mélanie, Lacabaratz, Christine, Beq, Stéphanie, Jarne, Ana, Croughs, Thérèse, Sekaly, Rafick-Pierre, Lederman, Michael M., Sereti, Irini, Commenges, Danie

Journal:

PLoS Computational Biology

Year:

2014

Language:

english

File:

PDF, 819 KB

english, 2014

37

A Paradoxical Treatment for a Paradoxical Condition: Infliximab Use in Three Cases of Mycobacterial IRIS: Figure 1.

Hsu, Denise C., Faldetta, Kimberly F., Pei, Luxin, Sheikh, Virginia, Utay, Netanya S., Roby, Gregg, Rupert, Adam, Fauci, Anthony S., Sereti, Irini

Journal:

Clinical Infectious Diseases

Year:

2015

Language:

english

File:

PDF, 266 KB

english, 2015

38

Response to Bandera et al: Table 1.

Wilson, Eleanor M. P., Hullsiek, Katherine Huppler, Sereti, Irini, Baker, Jason V.

Journal:

The Journal of Infectious Diseases

Year:

2015

Language:

english

File:

PDF, 46 KB

english, 2015

39

Clinically Indicated Corticosteroids Do Not Affect Bone Turnover During Immune Restoration of Severely Lymphopenic HIV-Infected Patients

Grant, Philip M., Sheikh, Virginia, DerSimonian, Rebecca, Rupert, Adam, Roby, Gregg, Pau, Alice, Sneller, Michael C., Rico, Sheryl-vi, Brown, Todd T., Sereti, Irini

Journal:

AIDS Research and Human Retroviruses

Year:

2015

Language:

english

File:

PDF, 187 KB

english, 2015

40

Prevalence of Strongyloides stercoralis in an urban US AIDS cohort

Nabha, Linda, Krishnan, Sonya, Ramanathan, Roshan, Mejia, Rojelio, Roby, Gregg, Sheikh, Virginia, Mcauliffe, Isabel, Nutman, Thomas, Sereti, Irini

Journal:

Pathogens and Global Health

Year:

2012

Language:

english

File:

PDF, 200 KB

english, 2012

41

Repeated Cycles of Recombinant Human Interleukin-7 in HIV-Infected Patients with low CD4 T cell Reconstitution on Antiretroviral Therapy: Results of two Phase II Multicentre Studies

Thiébaut, Rodolphe, Jarne, Ana, Routy, Jean-Pierre, Sereti, Irini, Fischl, Margaret, Ive, Prudence, Speck, Roberto F., D'Offizi, Gianpiero, Casari, Salvatore, Commenges, Daniel, Foulkes, Sharne, Natar

Journal:

Clinical Infectious Diseases

Year:

2016

Language:

english

File:

PDF, 1.77 MB

english, 2016

42

Serious Non-AIDS Events: Therapeutic Targets of Immune Activation and Chronic Inflammation in HIV Infection

Hsu, Denise C., Sereti, Irini

Journal:

Year:

2016

Language:

english

File:

PDF, 1.14 MB

english, 2016

43

Incomplete CD4 T Cell Recovery in HIV-1 Infection After 12 Months of Highly Active Antiretroviral Therapy Is Associated With Ongoing Increased CD4 T Cell Activation and Turnover

Anthony, Kara B., Yoder, Christian, Metcalf, Julia A., DerSimonian, Rebecca, Orenstein, Jan M., Stevens, Randy A., Falloon, Judy, Polis, Michael A., Lane, H. Clifford, Sereti, Irini

Journal:

JAIDS Journal of Acquired Immune Deficiency Syndromes

Year:

2003

File:

PDF, 6.21 MB

2003

44

Delayed Sample Processing Leads to Marked Decreases in Measured Plasma IL-7 Levels

Read, Sarah W., Rupert, Adam, Stevens, Randy, O'Shea, Angeline, Sereti, Irini

Journal:

JAIDS Journal of Acquired Immune Deficiency Syndromes

Year:

2006

Language:

english

File:

PDF, 187 KB

english, 2006

45

Vitamin D, d-dimer, Interferon γ, and sCD14 Levels are Independently Associated with Immune Reconstitution Inflammatory Syndrome: A Prospective, International Study

Musselwhite, Laura W., Andrade, Bruno B., Ellenberg, Susan S., Tierney, Ann, Belaunzaran-Zamudio, Pablo F., Rupert, Adam, Lederman, Michael M., Sanne, Ian, Sierra Madero, Juan G., Sereti, Irini

Journal:

Year:

2016

Language:

english

File:

PDF, 1.04 MB

english, 2016

46

Inferiority of IL-2 alone versus IL-2 with HAART in maintaining CD4 T cell counts during HAART interruption: a randomized controlled trial

Porter, Brian O, Anthony, Kara B, Shen, Jean, Hahn, Barbara, Keh, Chris E, Maldarelli, Frank, Blackwelder, William C, Lane, Henry Clifford, Kovacs, Joseph A, Davey, Richard T, Sereti, Irini

Journal:

Year:

2009

Language:

english

File:

PDF, 253 KB

english, 2009

47

Interruption of antiretroviral therapy blunts but does not abrogate CD4 T-cell responses to interleukin-2 administration in HIV infected patients

Keh, Chris E, Shen, Jean M, Hahn, Barbara, Hallahan, Claire W, Rehm, Catherine A, Thaker, Vishakha, Wynne, Sarah M, Davey, Richard T, Lane, H Clifford, Sereti, Irini

Journal:

Year:

2006

Language:

english

File:

PDF, 302 KB

english, 2006

48

CD4 T cell expansions are associated with increased apoptosis rates of T lymphocytes during IL-2 cycles in HIV infected patients

Sereti, Irini, Herpin, Betsey, Metcalf, Julia A., Stevens, Randy, Baseler, Michael W., Hallahan, Claire W., Kovacs, Joseph A., Davey, Richard T., Lane, H. Clifford

Journal:

Year:

2001

Language:

english

File:

PDF, 380 KB

english, 2001

49

HIV-1 viruses detected during episodic blips following interleukin-7 administration are similar to the viruses present before and after interleukin-7 therapy

Imamichi, Hiromi, DeGray, Gerald, Asmuth, David M, Fischl, Margaret A, Landay, Alan L, Lederman, Michael M, Sereti, Irini

Journal:

Year:

2011

Language:

english

File:

PDF, 168 KB

english, 2011

50

Interleukin-2 cycling causes transient increases in high-sensitivity C-reactive protein and D-dimer that are not associated with plasma HIV-RNA levels

Porter, Brian O, Shen, Jean, Kovacs, Joseph A, Davey, Richard T, Rehm, Catherine, Lozier, Jay, Csako, Gyorgy, Nghiem, Khanh, Costello, Rene, Lane, Henry Clifford, Sereti, Irini

Journal:

Year:

2009

Language:

english

File:

PDF, 229 KB

english, 2009